Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788461 | 0.90 | AURKA (0.41) | LOXL2AURKARPS6KB1KDM4EKDM5C | |
| SCHEMBL12788103 | 0.89 | AURKA (0.36) | LOXL2AURKARPS6KB1PLAAT3PLAAT5 | |
| SCHEMBL12788779 | 0.88 | HTT (0.42) | LOXL2AURKARPS6KB1KDM4ETP53 | |
| SCHEMBL12788724 | 0.87 | AURKA (0.37) | LOXL2AURKARPS6KB1KDM4EPLAAT3 | |
| SCHEMBL12788812 | 0.87 | AURKA (0.37) | LOXL2AURKARPS6KB1KDM5BPLAAT3 | |
| SCHEMBL12811364 | 0.86 | OPRM1 (0.50) | P2RX3CNR1CNR2AURKARPS6KB1 | |
| SCHEMBL12788768 | 0.86 | AURKA (0.36) | LOXL2AURKARPS6KB1KDM5BPLAAT3 | |
| SCHEMBL12788098 | 0.84 | TP53 (0.38) | LOXL2AURKARPS6KB1KDM4ETP53 | |
| SCHEMBL12811543 | 0.84 | TP53 (0.41) | AURKARPS6KB1KDM4ETP53MAP2K7 | |
| SCHEMBL1437346 | 0.84 | TP53 (0.39) | AURKARPS6KB1KDM4ETP53MAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |