Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | WNT3A | P56704 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443172 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442767 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL12812516 | 0.88 | WNT3A (0.46) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442104 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442323 | 0.84 | MCHR1 (0.47) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1443409 | 0.84 | MAPT (0.56) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442689 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442230 | 0.83 | MCHR1 (0.45) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT | |
| SCHEMBL1442532 | 0.83 | WNT3A (0.49) | WNT3AKDM4EALDH1A1MAPTNR4A1 | |
| SCHEMBL1443678 | 0.83 | KDM4E (0.44) | SMN1; SMN2WNT3AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026579-A1 | SUBSTITUTED AMINOQUINOXALINES AS TYROSINE THREONINE KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-10 | — | — | WO | disclosed |