Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443118 | 0.91 | WNT3A (0.45) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1442384 | 0.90 | WNT3A (0.44) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1443019 | 0.89 | WNT3A (0.43) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1443409 | 0.88 | MAPT (0.56) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL12812484 | 0.88 | SMN1; SMN2 (0.46) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1443105 | 0.87 | SLC2A1 (0.49) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1442689 | 0.87 | SMN1; SMN2 (0.56) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1442323 | 0.87 | MCHR1 (0.47) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL12812498 | 0.87 | WNT3A (0.48) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1443467 | 0.86 | KMT2A (0.54) | WNT3ASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026579-A1 | SUBSTITUTED AMINOQUINOXALINES AS TYROSINE THREONINE KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-03-10 | — | — | WO | disclosed |