Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.69 |
| ▸ | IGF1R | P08069 | 2/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.67 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PPM1G | O15355 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.59 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657757 | 0.92 | INSR (0.69) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL12812715 | 0.85 | MEN1 (0.82) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL29665101 | 0.85 | MEN1 (0.82) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL3362325 | 0.85 | MEN1 (0.82) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL3362327 | 0.85 | MEN1 (0.82) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL3363658 | 0.82 | IGF1R (1.00) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL12989670 | 0.82 | IGF1R (1.00) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL3363656 | 0.82 | IGF1R (1.00) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL3364888 | 0.81 | PIK3CG (1.00) | INSRIGF1RPIK3CGPTP4A3PIK3CA | |
| SCHEMBL12989666 | 0.81 | PIK3CG (1.00) | INSRIGF1RPIK3CGPTP4A3PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802297-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASE CAUSED BY YERSINIA SPP INFECTION | BURNHAM INST (US) | 2011-03-30 | — | — | EP | disclosed |
| US-20090312352-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASE CAUSED BY YERSINIA SPP INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-17 | — | — | US | disclosed |
| US-20090312352-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASE CAUSED BY YERSINIA SPP INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312352-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASE CAUSED BY YERSINIA SPP INFECTION | PTPRS, PTPRO, PTPN5 | INSR 2461/4885IGF1R 2923/4885PIK3CG 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.