Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | INSR | P06213 | 2/20 | 0.69 |
| ▸ | IGF1R | P08069 | 2/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.64 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ITGAM | P11215 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812715 | 1.00 | MEN1 (0.82) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3362325 | 1.00 | MEN1 (0.82) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3362327 | 1.00 | MEN1 (0.82) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL30657757 | 0.87 | INSR (0.69) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL13236142 | 0.85 | IGF1R (0.74) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3890812 | 0.85 | IGF1R (0.74) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3890807 | 0.85 | IGF1R (0.74) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL12812667 | 0.85 | INSR (0.69) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL12990164 | 0.82 | MEN1 (0.58) | MEN1POLBKMT2ATDP1L3MBTL1 | |
| SCHEMBL3363029 | 0.82 | MEN1 (0.58) | MEN1POLBKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250312367-A1 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-10-09 | — | — | US | disclosed |
| EP-4522628-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220737-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-110272388-B | 4-dithioformic acid piperazine-3-nitro-1, 8-naphthalimide derivative and synthesis method and application thereof | 桂林医学院 | 2022-06-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250312367-A1 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | POLRMT, TARDBP, NSUN2 | MEN1 1631/4885POLB 20/4885KMT2A 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.