Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317527 | 0.77 | PRKCZ (0.34) | — | |
| SCHEMBL12107535 | 0.76 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL13773381 | 0.71 | — | — | |
| SCHEMBL12975314 | 0.70 | — | — | |
| SCHEMBL14289956 | 0.56 | KDM4E (0.36) | — | |
| SCHEMBL26597079 | 0.55 | POLB (0.34) | — | |
| SCHEMBL26596858 | 0.54 | — | — | |
| SCHEMBL22062337 | 0.53 | — | — | |
| SCHEMBL26596874 | 0.50 | — | — | |
| SCHEMBL22624042 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029046-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |