SCHEMBL12815686

SCHEMBL12815686

Cc1cc([Si](C)(C)C)cc([Si](C)(Cl)c2cc(C)ccc2C)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12814757 0.91 ALDH1A1 (0.34) ALDH1A1TDP1RAPGEF4
SCHEMBL12816389 0.86 TP53 (0.31) TDP1RAPGEF4
SCHEMBL12816253 0.86 ALDH1A1 (0.31) ALDH1A1TDP1RAPGEF4
SCHEMBL12816653 0.83 TSHR (0.30)
SCHEMBL1313505 0.81 TDP1 (0.41) ALDH1A1TDP1RAPGEF4
SCHEMBL12815737 0.80 TDP1 (0.31) ALDH1A1TDP1
SCHEMBL12817969 0.79
SCHEMBL1315846 0.79 NQO2 (0.34) ALDH1A1TDP1
SCHEMBL12816757 0.78 TDP1 (0.32) ALDH1A1TDP1
SCHEMBL12817340 0.77 RAPGEF4 (0.33) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012133929-A1 METHOD FOR PRODUCING THE TRANSITION METAL ION COMPLEX, CATALYST FOR TRIMERIZATION, AND METHOD FOR PRODUCING 1-HEXENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed