Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482151 | 0.70 | DAO (1.00) | DAOAKR1C3AKR1C2 | |
| SCHEMBL1460498 | 0.68 | MAOA (0.53) | — | |
| SCHEMBL5133924 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL353863 | 0.66 | ALOX5 (0.38) | DAO | |
| SCHEMBL30716975 | 0.64 | DAO (0.53) | DAOAKR1C3AKR1C2 | |
| SCHEMBL2873532 | 0.64 | — | — | |
| SCHEMBL12432742 | 0.64 | DAO (0.53) | DAOAKR1C3AKR1C2CTNNB1TCF7L2 | |
| SCHEMBL31538134 | 0.64 | DAO (0.53) | DAOAKR1C3AKR1C2 | |
| SCHEMBL482202 | 0.64 | DAO (0.53) | DAOAKR1C3AKR1C2 | |
| SCHEMBL14644667 | 0.64 | DAO (0.53) | DAOAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2012131297-A1 | PYRIDO [3',2' :4,5] THIENO [3, 2-D] PYRIMIDIN- 4 - YLAMINE DERIVATIVES AND THEIR THERAPEUTICAL USE | BAELL JONATHAN BAYLDON (AU) | 2012-10-04 | — | — | WO | disclosed |