Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 8/20 | 0.42 |
| ▸ | BRD2 | P25440 | 6/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819074 | 0.85 | CYP2C9 (0.51) | MAPTMEN1KMT2AKDM2BCYP2C9 | |
| SCHEMBL12818629 | 0.83 | HTR6 (0.41) | MAPTMEN1KMT2AKDM2BCYP2C9 | |
| SCHEMBL12817919 | 0.83 | BRD4 (0.41) | BRD4BRD2BRD3KDM2BDRD2 | |
| SCHEMBL12818722 | 0.83 | KDM2B (0.41) | MAPTMEN1KMT2AKDM2BCYP2C9 | |
| SCHEMBL12818382 | 0.81 | MAPT (0.44) | MAPTBRD4BRD2BRD3MEN1 | |
| SCHEMBL12817704 | 0.81 | KDM2B (0.40) | MAPTMEN1KMT2AKDM2BCYP2C9 | |
| SCHEMBL12818708 | 0.81 | BRD4 (0.45) | MAPTBRD4BRD2BRD3MEN1 | |
| SCHEMBL12819192 | 0.80 | MEN1 (0.40) | MAPTMEN1KMT2AKDM2BCYP2C9 | |
| SCHEMBL12818102 | 0.80 | BRD4 (0.45) | MAPTBRD4BRD2BRD3MEN1 | |
| SCHEMBL12818264 | 0.79 | PDE3B (0.39) | MAPTMEN1KMT2AKDM2BCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |