Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444741 | 0.89 | QPCT (0.44) | QPCTQPCTLABL1KMT2ARIN1 | |
| SCHEMBL1444755 | 0.75 | QPCT (0.51) | QPCTQPCTLMDM4MDM2 | |
| SCHEMBL1444367 | 0.71 | QPCT (0.68) | QPCTQPCTLKMT2A | |
| SCHEMBL1445244 | 0.69 | QPCT (0.66) | QPCTQPCTL | |
| SCHEMBL12732479 | 0.69 | QPCT (0.45) | QPCTQPCTLMMP12ABL1KMT2A | |
| SCHEMBL16864409 | 0.69 | QPCT (0.46) | QPCT | |
| SCHEMBL16864397 | 0.69 | QPCT (0.48) | QPCTQPCTLMDM2 | |
| SCHEMBL1444694 | 0.69 | QPCT (0.47) | QPCTQPCTLMMP12 | |
| SCHEMBL1444517 | 0.67 | QPCT (0.46) | QPCTQPCTLMMP12ABL1KMT2A | |
| SCHEMBL12819253 | 0.67 | QPCT (0.68) | QPCTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029920-A1 | HETEROCYLCIC DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2011-03-17 | — | — | WO | disclosed |