Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286997 | 0.87 | KCNH2 (0.56) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL114931 | 0.87 | KCNH2 (0.56) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL12812920 | 0.85 | KCNH2 (0.58) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL12814244 | 0.85 | KCNH2 (0.53) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL12812917 | 0.83 | ALDH1A1 (0.58) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| Trifluoroacetic Acid SCHEMBL144426 | 0.83 | KCNH2 (0.53) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL116490 | 0.82 | KCNH2 (0.53) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL12836902 | 0.82 | KCNH2 (0.55) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL12812912 | 0.81 | ALDH1A1 (0.56) | KCNH2LMNAALDH1A1POLBOPRM1 | |
| SCHEMBL12819497 | 0.81 | LMNA (0.54) | KCNH2LMNAALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031744-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |