Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152632 | 0.83 | CNR2 (0.43) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL9152644 | 0.83 | CNR2 (0.43) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL10216472 | 0.82 | HSD11B1 (0.36) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL10216435 | 0.82 | HSD11B1 (0.36) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL10216456 | 0.82 | HSD11B1 (0.36) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL10216590 | 0.82 | HSD11B1 (0.36) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL3898662 | 0.81 | HSD11B1 (0.38) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL3898665 | 0.81 | HSD11B1 (0.38) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL7024082 | 0.78 | CNR2 (0.44) | HSD11B1CNR1CNR2POLBSPHK1 | |
| SCHEMBL7679006 | 0.78 | CNR2 (0.44) | HSD11B1CNR1CNR2POLBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029915-A1 | ETHER DERIVATIVES OF BICYCLIC HETEROARYLS | NOVARTIS AG (CH) | 2011-03-17 | — | — | WO | disclosed |