Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820529 | 0.81 | MAPT (0.41) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL14311717 | 0.74 | PGR (0.46) | MAPTLMNAALDH1A1MAPK1TSHR | |
| SCHEMBL28257651 | 0.73 | MAPK1 (0.49) | MAPTPKMESR1CYP19A1ESR2 | |
| SCHEMBL10477098 | 0.70 | GSK3B (0.51) | MAPTPKMGAAGSK3BKMT2A | |
| SCHEMBL29245311 | 0.69 | MAOB (0.45) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL30937420 | 0.69 | MAOB (0.45) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL28872876 | 0.68 | PKM (0.62) | MAPTPKMGAAGSK3BKMT2A | |
| SCHEMBL21560519 | 0.68 | CYP3A4 (0.45) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL10477111 | 0.68 | ABCG2 (0.49) | MAPTPKMGAAGSK3BKMT2A | |
| SCHEMBL5049796 | 0.68 | TDP1 (0.41) | MAPTGAAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910921-B2 | diodes comprising 2-[7'-(2-mercapto-ethylamino)-9,9,9',9'-tetramethyl-9H,9'H-[2,2']bifluoreny-7-yl]-1-(4-nitro-phenyl)-ethanone, in contact with electrodes; rectifiers; microelectronics | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20080224131-A1 | Compound, a molecular switch employing the compound and a method of electronic switching | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-09-18 | — | — | US | disclosed |
| US-7378539-B2 | Compound, a molecular switch employing the compound and a method of electronic switching | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080224131-A1 | Compound, a molecular switch employing the compound and a method of electronic switching | BRD4, BICRA, BRD3 | MAPT 1829/4885PKM 2131/4885ESR1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.