Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174148 | 0.93 | PDK2 (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31408561 | 0.93 | MAPT (0.45) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14305890 | 0.93 | MAPT (0.45) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14174130 | 0.91 | MAPT (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14508381 | 0.89 | PDK2 (0.40) | ALDH1A1PDK2PGRCYP3A4TSHR | |
| SCHEMBL1649907 | 0.89 | PDK2 (0.40) | ALDH1A1PDK2PGRCYP3A4TSHR | |
| SCHEMBL1648023 | 0.89 | PDK2 (0.40) | ALDH1A1PDK2PGRCYP3A4TSHR | |
| SCHEMBL14508377 | 0.88 | PDK2 (0.39) | ALDH1A1PDK2PGRMAPK1TDP2 | |
| SCHEMBL29721570 | 0.86 | TDP2 (0.40) | ALDH1A1PDK2PGRMAPK1TDP2 | |
| SCHEMBL824163 | 0.86 | TDP2 (0.40) | ALDH1A1PDK2PGRMAPK1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910921-B2 | diodes comprising 2-[7'-(2-mercapto-ethylamino)-9,9,9',9'-tetramethyl-9H,9'H-[2,2']bifluoreny-7-yl]-1-(4-nitro-phenyl)-ethanone, in contact with electrodes; rectifiers; microelectronics | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20080224131-A1 | Compound, a molecular switch employing the compound and a method of electronic switching | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080224131-A1 | Compound, a molecular switch employing the compound and a method of electronic switching | BRD4, BICRA, BRD3 | ALDH1A1 1934/4885KDM4E 1350/4885MEN1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.