SCHEMBL1649907

SCHEMBL1649907

CC1(C)c2cc(Br)ccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(Br)ccc3-4)cc21

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.40
PGR P06401 7/20 0.36
S100A4 P26447 1/20 0.35
TDP2 O95551 3/20 0.35
AKR1A1 P14550 1/20 0.35
AKR1B1 P15121 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
METAP1 P53582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648023 1.00 PDK2 (0.40) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL14508381 1.00 PDK2 (0.40) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL14508377 0.98 PDK2 (0.39) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL29721570 0.96 TDP2 (0.40) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL824163 0.96 TDP2 (0.40) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL14447186 0.94 PDK2 (0.37) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL824234 0.92 TDP2 (0.42) PDK2PGRTDP2NPC1RAB9A
SCHEMBL29403081 0.91 PDK2 (0.44) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL29587737 0.91 PDK2 (0.44) PDK2PGRS100A4TDP2AKR1A1
SCHEMBL204806 0.91 PDK2 (0.44) PDK2PGRS100A4TDP2AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2306541-B1 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORP (JP) 2018-10-24 EP disclosed
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
EP-1532089-B1 FLUORENE COMPOUND AND ORGANIC LUMINESCENT DEVICE USING THE SAME CANON KK (JP) 2017-03-29 EP disclosed
US-9412952-B2 Photoelectric conversion element and method of using the same, image sensor, and optical sensor FUJIFILM CORPORATION (JP) 2016-08-09 US disclosed
US-9412952-B2 Photoelectric conversion element and method of using the same, image sensor, and optical sensor FUJIFILM CORPORATION (JP) 2016-08-09 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20140158859-A1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD OF USING THE SAME, IMAGE SENSOR, AND OPTICAL SENSOR FUJIFILM CORPORATION (JP) 2014-06-12 US disclosed
CN-102024907-A Photoelectric conversion device, method for producing same, photosensor, imaging device, and method for driving same FUJIFILM CORP 2011-04-20 CN disclosed
EP-2306541-A1 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods Fujifilm Corporation (JP) 2011-04-06 EP disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20090179551-A1 Organic Electroluminescent Compounds and Display Device Using the Same GRACEL DISPLAY INC. (KP) 2009-07-16 US disclosed
US-20090179551-A1 Organic Electroluminescent Compounds and Display Device Using the Same GRACEL DISPLAY INC. (KP) 2009-07-16 US disclosed
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-07 US disclosed
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-07 US disclosed
US-7241513-B2 Fluorene compound and organic luminescent device using the same CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
US-7241513-B2 Fluorene compound and organic luminescent device using the same CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
WO-2007061218-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND DISPLAY DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090179551-A1 Organic Electroluminescent Compounds and Display Device Using the Same OCIAD2, OCIAD1, ICOSLG PDK2 1598/4885PGR 4203/4885S100A4 2442/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO PDK2 196/4885PGR 988/4885S100A4 934/4885
US-20090115323-A1 OLIGOFLUORENE COMPOUND AND ORGANIC EL ELEMENT USING SAME ELP1, LEF1, ELAVL1 PDK2 3735/4885PGR 1924/4885S100A4 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.