Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820601 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TP53PTPN1DUSP3 | |
| SCHEMBL12820597 | 0.82 | DGKA (0.44) | MAPTALDH1A1HPGDFAAH | |
| SCHEMBL5358635 | 0.81 | EP300 (0.46) | TOP1PPARGMAPTFABP4BLM | |
| SCHEMBL5358639 | 0.81 | EP300 (0.46) | TOP1PPARGMAPTFABP4BLM | |
| SCHEMBL5365746 | 0.79 | GRIK1 (0.42) | MAPTFABP4BLMHSD17B10USP2 | |
| SCHEMBL5365750 | 0.79 | GRIK1 (0.42) | MAPTFABP4BLMHSD17B10USP2 | |
| SCHEMBL28895848 | 0.78 | ACE2 (0.46) | FFAR4FFAR1PPARGPPARDPTPN1 | |
| SCHEMBL7949343 | 0.77 | PPARG (0.63) | TOP1FFAR4FFAR1PPARGMAPT | |
| SCHEMBL8382908 | 0.77 | PPARG (0.63) | TOP1FFAR4FFAR1PPARGMAPT | |
| SCHEMBL7949394 | 0.77 | PPARG (0.63) | TOP1FFAR4FFAR1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029099-A1 | COMPOUNDS FOR TREATING DISORDERS OR DISEASES ASSOCIATED WITH NEUROKININ 2 RECEPTOR ACTIVITY | UNITED PARAGON ASSOCIATES INC. (CA) | 2011-03-10 | — | — | WO | disclosed |