Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | POLA1 | P09884 | 4/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499400 | 1.00 | ALOX15 (0.34) | ALOX15ALOX12POLA1CETPHRH2 | |
| SCHEMBL16499480 | 0.79 | AKR1B1 (0.36) | — | |
| SCHEMBL12813268 | 0.76 | CYP3A4 (0.44) | POLA1 | |
| SCHEMBL16499505 | 0.76 | CYP3A4 (0.42) | ALOX15ALOX12POLA1 | |
| SCHEMBL12821663 | 0.76 | CYP3A4 (0.42) | ALOX15ALOX12POLA1 | |
| SCHEMBL16499567 | 0.76 | TRPA1 (0.39) | CETP | |
| SCHEMBL16499383 | 0.76 | TRPA1 (0.39) | CETP | |
| SCHEMBL16499264 | 0.71 | TRPA1 (0.35) | CETPPIK3CAPIK3CG | |
| SCHEMBL12825623 | 0.71 | TRPA1 (0.35) | CETPPIK3CAPIK3CG | |
| SCHEMBL9880742 | 0.71 | ALOX15 (0.48) | ALOX15ALOX12POLA1CETPPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |