Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601040 | 0.82 | SMN1; SMN2 (0.50) | RAB9AGAANPC1TP53SMN1; SMN2 | |
| SCHEMBL11477612 | 0.81 | ALDH1A1 (0.55) | RAB9AGAANPC1SMN1; SMN2POLB | |
| SCHEMBL25528975 | 0.80 | TSHR (0.50) | RAB9AGAANPC1SMN1; SMN2MAPT | |
| SCHEMBL6240285 | 0.78 | SMN1; SMN2 (0.46) | RAB9AGAANPC1TP53SMN1; SMN2 | |
| SCHEMBL11477607 | 0.78 | TSHR (0.51) | RAB9AGAANPC1ADORA1SMN1; SMN2 | |
| SCHEMBL12191262 | 0.78 | — | — | |
| SCHEMBL9547521 | 0.77 | SMN1; SMN2 (0.56) | RAB9AGAANPC1TP53ADORA3 | |
| SCHEMBL1258860 | 0.77 | HPGD (0.50) | RAB9AGAANPC1SMN1; SMN2MAPT | |
| SCHEMBL3483318 | 0.75 | — | — | |
| SCHEMBL21765881 | 0.75 | GAA (0.46) | RAB9AGAANPC1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130299-A1 | PEPTIDASE INHIBITORS | PROZYMEX A/S (DK) | 2012-10-04 | — | — | WO | disclosed |