Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601040 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4CALDH1A1RAB9ATAAR1 | |
| SCHEMBL12822285 | 0.78 | RAB9A (0.57) | SMN1; SMN2KDM4CALDH1A1RAB9ANPC1 | |
| SCHEMBL9547521 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4CALDH1A1RAB9ATAAR1 | |
| SCHEMBL25528975 | 0.73 | TSHR (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL3483318 | 0.72 | — | — | |
| SCHEMBL11477612 | 0.71 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL12191262 | 0.71 | — | — | |
| SCHEMBL11765049 | 0.71 | — | — | |
| SCHEMBL1258860 | 0.70 | HPGD (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL7942015 | 0.69 | CYP3A4 (0.66) | SMN1; SMN2MTNR1BTP53GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077928-B1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2005-12-07 | — | — | EP | disclosed |