Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23260542 | 0.77 | F12 (0.52) | MEN1KMT2AHIF1AGAAALOX12 | |
| SCHEMBL10140987 | 0.76 | PLAU (0.32) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL23260538 | 0.75 | KDM4E (0.54) | MEN1KMT2AHTTPTGS1ALDH1A1 | |
| SCHEMBL20878620 | 0.74 | PLAU (0.63) | UGT2B7HTTF2PLGPLAU | |
| Hydrogen Peroxide SCHEMBL9172508 | 0.73 | UGT2B7 (0.60) | UGT2B7MEN1KMT2AATMHTT | |
| Hydrogen Peroxide SCHEMBL9840257 | 0.73 | UGT2B7 (0.60) | UGT2B7MEN1KMT2AATMHTT | |
| SCHEMBL181347 | 0.73 | UGT2B7 (0.58) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL30031337 | 0.73 | UGT2B7 (0.58) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL10457062 | 0.72 | CYP2A6 (0.56) | UGT2B7MEN1KMT2AMMP9PTGS1 | |
| SCHEMBL8081677 | 0.72 | KDM4E (0.55) | UGT2B7EIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |