Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23260542 | 0.79 | F12 (0.52) | MEN1KMT2ANPC1CYP1A2CYP2C19 | |
| SCHEMBL10140987 | 0.77 | PLAU (0.32) | PLAU | |
| SCHEMBL12824538 | 0.75 | UGT2B7 (0.41) | MEN1KMT2ACYP1A2ALDH1A1PLAU | |
| SCHEMBL13811105 | 0.73 | KDM4E (0.51) | KDM4EMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL31546801 | 0.73 | PRSS1 (0.68) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL3368290 | 0.73 | PRSS1 (0.68) | KDM4ECYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL17288621 | 0.72 | KDM4E (0.63) | KDM4EMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL11810869 | 0.72 | KDM4E (0.75) | KDM4EMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL29447161 | 0.72 | CYP1A2 (0.79) | KDM4EMEN1KMT2ANPC1CYP1A2 | |
| SCHEMBL443070 | 0.72 | CYP1A2 (0.79) | KDM4EMEN1KMT2ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076617-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-22 | — | — | WO | disclosed |