Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12824722 | 0.87 | SMO (0.43) | SMOEPHX2IRAK4 | |
| SCHEMBL12824727 | 0.87 | SMO (0.45) | SMOEPHX2IRAK4MEN1ALDH1A1 | |
| SCHEMBL10004214 | 0.86 | SMO (0.47) | SMOEPHX2IRAK4ALKCD274 | |
| SCHEMBL12825027 | 0.85 | SMO (0.43) | SMOEPHX2IRAK4ALDH1A1 | |
| SCHEMBL12825060 | 0.85 | SMO (0.43) | SMOEPHX2MEN1ALDH1A1KMT2A | |
| SCHEMBL12825026 | 0.84 | SMO (0.43) | SMOEPHX2IRAK4 | |
| SCHEMBL12825061 | 0.84 | SMO (0.46) | SMOEPHX2 | |
| SCHEMBL12824853 | 0.82 | SMO (0.39) | SMOEPHX2 | |
| SCHEMBL12825019 | 0.82 | SMO (0.44) | SMOEPHX2MEN1ALDH1A1KMT2A | |
| SCHEMBL12825023 | 0.81 | SMO (0.42) | SMOEPHX2ALKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |