Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 3/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825027 | 0.92 | SMO (0.43) | SMOEPHX2MAPTALDH1A1 | |
| SCHEMBL12825023 | 0.91 | SMO (0.42) | SMOKMT2AEPHX2MEN1 | |
| SCHEMBL12824594 | 0.89 | SMO (0.43) | SMOKMT2AEPHX2MAPTHPGDS | |
| SCHEMBL12825026 | 0.88 | SMO (0.43) | SMOEPHX2MAPT | |
| SCHEMBL12824722 | 0.87 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824727 | 0.87 | SMO (0.45) | SMOKMT2AEPHX2MEN1L3MBTL1 | |
| SCHEMBL10003581 | 0.86 | SMO (0.51) | SMOKMT2AEPHX2MEN1L3MBTL1 | |
| SCHEMBL12825061 | 0.85 | SMO (0.46) | SMOEPHX2 | |
| SCHEMBL12824595 | 0.85 | SMO (0.41) | SMOKMT2AEPHX2MEN1ALDH1A1 | |
| SCHEMBL12824599 | 0.85 | SMO (0.40) | SMOKMT2AEPHX2MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |