Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.38 |
| ▸ | CDK2 | P24941 | 7/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825060 | 0.91 | SMO (0.43) | SMOEPHX2KMT2AMEN1 | |
| SCHEMBL12824594 | 0.90 | SMO (0.43) | SMOEPHX2KMT2A | |
| SCHEMBL10003070 | 0.86 | SMO (0.49) | SMOEPHX2CCNE1CDK2CDK4 | |
| SCHEMBL12824615 | 0.85 | SMO (0.44) | SMOEPHX2 | |
| SCHEMBL12824722 | 0.85 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12825061 | 0.84 | SMO (0.46) | SMOEPHX2 | |
| SCHEMBL12824727 | 0.83 | SMO (0.45) | SMOEPHX2KMT2AMEN1 | |
| SCHEMBL12825027 | 0.83 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12825055 | 0.83 | SMO (0.44) | SMOEPHX2 | |
| SCHEMBL12824862 | 0.83 | SMO (0.44) | SMOEPHX2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |