Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420933 | 0.88 | UCHL1 (0.38) | POLBUCHL1AOC3GPR119CHRNA7 | |
| SCHEMBL15553247 | 0.84 | POLB (0.43) | POLBUCHL1GPR119CHRNA7GRM5 | |
| SCHEMBL29736736 | 0.84 | POLB (0.43) | POLBUCHL1GPR119CHRNA7GRM5 | |
| SCHEMBL31067862 | 0.81 | UCHL1 (0.40) | POLBUCHL1GPR119CHRNA7ACHE | |
| SCHEMBL21855821 | 0.81 | UCHL1 (0.47) | POLBUCHL1GPR119CHRNA7GRM5 | |
| SCHEMBL21856164 | 0.81 | UCHL1 (0.40) | POLBUCHL1GPR119CHRNA7ACHE | |
| SCHEMBL22121634 | 0.81 | UCHL1 (0.38) | POLBUCHL1GPR119CHRNA7ACHE | |
| SCHEMBL30746650 | 0.81 | UCHL1 (0.47) | POLBUCHL1GPR119CHRNA7GRM5 | |
| SCHEMBL2023466 | 0.78 | UCHL1 (0.48) | UCHL1GPR119HDAC1HDAC6 | |
| SCHEMBL30376147 | 0.78 | UCHL1 (0.48) | UCHL1GPR119HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023081-A1 | 5,6-BICYCLIC HETEROARYL-CONTAINING UREA COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2011-03-03 | — | — | WO | disclosed |