Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21856164 | 1.00 | UCHL1 (0.40) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL30746650 | 0.84 | UCHL1 (0.47) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL22121634 | 0.84 | UCHL1 (0.38) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL29736736 | 0.84 | POLB (0.43) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL21855821 | 0.84 | UCHL1 (0.47) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL15553247 | 0.84 | POLB (0.43) | UCHL1POLBGRM5GRM1CHRNA7 | |
| SCHEMBL31420933 | 0.81 | UCHL1 (0.38) | UCHL1POLBGRM5CHRNA7GPR119 | |
| SCHEMBL12825342 | 0.81 | POLB (0.38) | UCHL1POLBGRM5CHRNA7GPR119 | |
| SCHEMBL31600997 | 0.77 | USP30 (0.40) | UCHL1POLBGRM5CHRNA7GPR119 | |
| SCHEMBL30513272 | 0.76 | POLB (0.41) | UCHL1POLBGPR119ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066357-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2025-02-27 | — | — | US | disclosed |
| CN-114341124-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-09-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066357-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | PPM1A, PPM1F, PPP5C | UCHL1 2224/4885POLB 2558/4885GRM5 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.