⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644612 | 0.80 | — | — | |
| SCHEMBL27089533 | 0.76 | — | — | |
| SCHEMBL352571 | 0.75 | — | — | |
| SCHEMBL5392781 | 0.72 | NPC1 (0.59) | — | |
| SCHEMBL17760704 | 0.71 | — | — | |
| SCHEMBL16588061 | 0.70 | CTSK (0.38) | — | |
| SCHEMBL11107938 | 0.70 | — | — | |
| SCHEMBL15739263 | 0.67 | — | — | |
| SCHEMBL2239264 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL1150638 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | claimed |
| EP-1045856-B1 | NOVEL AROMATIC AMIDES, PREPARATION METHOD AND APPLICATION AS MEDICINES | AVENTIS PHARMA SA (FR) | 2003-04-09 | — | — | EP | claimed |
| US-20030060609-A1 | Novel aromatic amides, preparation method and application as medicines | AVENTIS PHARMA S.A. | 2003-03-27 | — | — | US | claimed |
| US-6420538-B1 | COMPOUND FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | claimed |
| US-11192918-B2 | Multicyclic peptides and methods for their preparation | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2021-12-07 | — | — | US | disclosed |
| US-20200239516-A1 | Multicyclic Peptides and Methods for Their Preparation | UNIVERSITEIT VAN AMSTERDAM (NL) | 2020-07-30 | — | — | US | disclosed |
| EP-3551642-A1 | MULTICYCLIC PEPTIDES AND METHODS FOR THEIR PREPARATION | Stichting voor de Technische Wetenschappen (NL) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018106112-A1 | MULTICYCLIC PEPTIDES AND METHODS FOR THEIR PREPARATION | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2018-06-14 | — | — | WO | disclosed |
| CN-107033164-A | Prepare the synthetic method of ecteinascidin compounds | 法马马有限公司 | 2017-08-11 | — | — | CN | disclosed |
| US-20170152287-A1 | METHODS AND COMPOSITIONS FOR SITE-SPECIFIC LABELING OF PEPTIDES AND PROTEINS | UNIVERSITY OF ROCHESTER | 2017-06-01 | — | — | US | disclosed |
| US-9557336-B2 | Methods and compositions for site-specific labeling of peptides and proteins | UNIVERSITY OF ROCHESTER (US) | 2017-01-31 | — | — | US | disclosed |
| US-9428524-B2 | Synthetic process for the manufacture of ecteinascidin compounds | PHARMA MAR, S.A. (ES) | 2016-08-30 | — | — | US | disclosed |
| WO-2010132029-A1 | OCTAHYDRO BIQUINOLINE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-11-18 | — | — | WO | disclosed |
| US-20100292163-A1 | Antitumoral Compounds | PHARMA MAR, S.A. (ES) | 2010-11-18 | — | — | US | disclosed |
| EP-2231695-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077401-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| EP-1045856-B1 | NOVEL AROMATIC AMIDES, PREPARATION METHOD AND APPLICATION AS MEDICINES | AVENTIS PHARMA SA (FR) | 2003-04-09 | — | — | EP | disclosed |
| US-20030060609-A1 | Novel aromatic amides, preparation method and application as medicines | AVENTIS PHARMA S.A. | 2003-03-27 | — | — | US | disclosed |
| US-6420538-B1 | COMPOUND FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | disclosed |