Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464983 | 0.75 | CHRM2 (0.59) | SCN8ACHRM2LTA4HEPHX2MPO | |
| Hydrochloric Acid SCHEMBL9764519 | 0.74 | CHRM2 (0.58) | SCN8ACHRM2LTA4HEPHX2MPO | |
| SCHEMBL3265257 | 0.72 | SIGMAR1 (0.70) | CHRM2LTA4HEPHX2MPOKDM4E | |
| Hydrochloric Acid SCHEMBL7320578 | 0.71 | SIGMAR1 (0.68) | CHRM2LTA4HEPHX2MPOKDM4E | |
| SCHEMBL10045186 | 0.71 | CHRM2 (0.88) | SCN8ACHRM2LMNAMPOKDM4E | |
| SCHEMBL15341674 | 0.71 | MAOA (0.62) | SCN8ACHRM2MEN1KMT2AKDM4E | |
| SCHEMBL14384235 | 0.70 | KMT2A (0.53) | SCN8ACHRM2MEN1KMT2ALMNA | |
| SCHEMBL21924124 | 0.70 | MAOA (0.73) | SCN8ACHRM2MEN1KMT2AMAPK1 | |
| SCHEMBL5149991 | 0.70 | DRD4 (0.77) | MEN1KMT2ALTA4HEPHX2 | |
| SCHEMBL10045185 | 0.69 | CHRM2 (0.92) | SCN8ACHRM2LMNAMPOMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915433-B2 | Tri-substituted 2-benzhydryl 5-benzlamino-tetrahydro-pyran-4-OL and 6-benzhydryl-4-benzylamino-tetrahydro-pyran-3-OL analogues, and novel 3,6 disubstituted pyran derivatives | WAYNE STATE UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |