⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175207 | 1.00 | — | — | |
| SCHEMBL19988476 | 1.00 | — | — | |
| SCHEMBL13807049 | 1.00 | — | — | |
| SCHEMBL5158025 | 0.97 | CA1 (0.36) | — | |
| SCHEMBL1274067 | 0.94 | — | — | |
| SCHEMBL1274061 | 0.94 | — | — | |
| SCHEMBL1274063 | 0.94 | — | — | |
| SCHEMBL1819105 | 0.82 | — | — | |
| SCHEMBL7130840 | 0.79 | GBA1 (0.32) | — | |
| SCHEMBL1560875 | 0.78 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289888-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |