⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829162 | 1.00 | — | — | |
| SCHEMBL19988476 | 1.00 | — | — | |
| SCHEMBL13807049 | 1.00 | — | — | |
| SCHEMBL5158025 | 0.97 | CA1 (0.36) | — | |
| SCHEMBL1274067 | 0.94 | — | — | |
| SCHEMBL1274061 | 0.94 | — | — | |
| SCHEMBL1274063 | 0.94 | — | — | |
| SCHEMBL1819105 | 0.82 | — | — | |
| SCHEMBL7130840 | 0.79 | GBA1 (0.32) | — | |
| SCHEMBL1560875 | 0.78 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351688-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers | ALCON INC. (CH) | 2025-07-08 | — | — | US | disclosed |
| US-12297323-B2 | Polysiloxane vinylic crosslinkers with high refractive index | ALCON INC. (CH) | 2025-05-13 | — | — | US | disclosed |
| EP-4314118-B1 | POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX | ALCON INC (CH) | 2025-04-30 | — | — | EP | disclosed |
| US-11945895-B2 | Photochromic polydiorganosiloxane vinylic crosslinkers | ALCON INC. (CH) | 2024-04-02 | — | — | US | disclosed |
| CN-115605529-B | Photochromic polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4118134-B1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| EP-4314118-A1 | POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | disclosed |
| EP-4291601-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | Alcon Inc. (CH) | 2023-12-20 | — | — | EP | disclosed |
| CN-116888193-A | Polysiloxane vinyl cross-linking agent with high refractive index | 爱尔康公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116867836-A | Hydrophilized polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| CN-101686665-A | styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2010-03-31 | — | — | CN | disclosed |
| EP-2076124-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ACUCELA INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ACUCELA INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170841-A1 | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders | ACUCELA INC. (US) | 2009-07-02 | — | — | US | disclosed |
| WO-2008131368-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008131368-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-1143300-A1 | Photoresist compositions and use of same | Shipley Company LLC (US) | 2001-10-10 | — | — | EP | disclosed |
| US-4574057-A | DICYCLOPENTADIENE, OLEFIN, FATTY ACID, GLYCOL MIXTURE AND POLYMER | NEVILLE CHEMICAL COMPANY (US) | 1986-03-04 | — | — | US | disclosed |