SCHEMBL12829249

SCHEMBL12829249

COC(=O)c1cccc(C(=O)NC(=O)c2ccccc2O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
LMNA P02545 1/20 0.56
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 2/20 0.51
MCOLN3 Q8TDD5 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51
PTPN11 Q06124 1/20 0.51
PKM P14618 1/20 0.51
MEN1 O00255 3/20 0.47
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
XDH P47989 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609242 0.86 NPC1 (0.63) TSHRLMNANPC1RAB9ACRHBP
SCHEMBL5309470 0.84 RAB9A (0.60) TSHRLMNANPC1RAB9AKMT2A
SCHEMBL9609214 0.83 NPC1 (0.53) LMNANPC1RAB9AKMT2APOLB
SCHEMBL10420732 0.83 LMNA (0.61) TSHRLMNANPC1RAB9AKMT2A
SCHEMBL15372570 0.83 NPC1 (0.55) LMNANPC1RAB9ACRHBPCRHR2
SCHEMBL9609272 0.80 RAB9A (0.53) NPC1RAB9ACRHBPCRHR2POLB
SCHEMBL19032011 0.79 NPC1 (0.70) LMNANPC1RAB9ACRHBPCRHR2
Ammonia Solution, Strong SCHEMBL28556515 0.79 TSHR (0.67) TSHRLMNANPC1RAB9AKMT2A
SCHEMBL7025048 0.77 HDAC8 (0.67) TSHRLMNANPC1RAB9AKMT2A
SCHEMBL30860438 0.77 HDAC8 (0.67) TSHRLMNANPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed