Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | KIF5B | P33176 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22938522 | 0.85 | SETD2 (0.38) | CYP1A2TDP1POLBKDM4EHRH3 | |
| SCHEMBL16809205 | 0.84 | MEN1 (0.43) | PIK3CDCYP1A2TDP1POLBKDM4E | |
| SCHEMBL20355941 | 0.84 | MEN1 (0.43) | PIK3CDCYP1A2TDP1POLBKDM4E | |
| SCHEMBL14826535 | 0.81 | OPRM1 (0.36) | PIK3CDCYP1A2TDP1EPHX2POLB | |
| SCHEMBL15450907 | 0.79 | CYP1A2 (0.46) | PIK3CDCYP1A2TDP1EPHX2POLB | |
| SCHEMBL19356002 | 0.77 | TDP1 (0.52) | PIK3CDCYP1A2TDP1KDM4EHRH3 | |
| SCHEMBL1441955 | 0.77 | CYP1A2 (0.45) | PIK3CDCYP1A2TDP1EPHX2POLB | |
| SCHEMBL12651153 | 0.76 | CHRM1 (0.45) | TDP1EPHX2POLBKDM4EEPHX1 | |
| SCHEMBL15508283 | 0.76 | CYP1A2 (0.52) | PIK3CDCYP1A2TDP1EPHX2POLB | |
| SCHEMBL23570938 | 0.76 | PIK3CD (0.44) | PIK3CDCYP1A2TDP1EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | MAP3K20, MAP3K1, PDPK1 | PIK3CD 71/4885CYP1A2 4806/4885TDP1 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.