SCHEMBL12829658

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1483838	1.00	SIRT5 (0.42)	SIRT5EPHX2ALDH1A1RAB9AKMT2A
	SCHEMBL1483837	1.00	SIRT5 (0.42)	SIRT5EPHX2ALDH1A1RAB9AKMT2A
	SCHEMBL1484314	0.92	EPHX2 (0.45)	EPHX2ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL13720393	0.92	EPHX2 (0.45)	EPHX2ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL1484315	0.92	EPHX2 (0.45)	EPHX2ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL17029112	0.90	SIRT5 (0.48)	SIRT5KMT2ATDP1NPSR1MEN1
	SCHEMBL1483360	0.89	SIRT5 (0.46)	SIRT5ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL1483361	0.89	SIRT5 (0.46)	SIRT5ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL12829974	0.89	SIRT5 (0.46)	SIRT5ALDH1A1RAB9AKMT2ATDP1
	SCHEMBL5738645	0.89	EPHX2 (0.42)	EPHX2ALDH1A1RAB9AKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.