Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775595 | 0.75 | POLB (0.36) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL23421921 | 0.74 | — | — | |
| SCHEMBL13157265 | 0.74 | POLB (0.34) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL27509924 | 0.73 | BRD4 (0.38) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL30050431 | 0.71 | POLB (0.39) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL12751319 | 0.70 | BRD4 (0.45) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL23637555 | 0.68 | — | — | |
| SCHEMBL609526 | 0.66 | ALDH1A1 (0.40) | POLBOPRM1SLC22A1SMN1; SMN2OPRD1 | |
| SCHEMBL12354409 | 0.66 | POLB (0.37) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 | |
| SCHEMBL27800390 | 0.64 | SMN1; SMN2 (0.38) | POLBBRD4OPRM1SLC22A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9272260-B2 | Methods of synthesis and purification by use of a solid support | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20110077393-A1 | METHODS OF SYNTHESIS AND PURIFICATION BY USE OF A SOLID SUPPORT | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077393-A1 | METHODS OF SYNTHESIS AND PURIFICATION BY USE OF A SOLID SUPPORT | WASF2, DCXR, RIOX2 | POLB 1741/4885BRD4 3465/4885OPRM1 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.