Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 5/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11924094 | 0.88 | PIM2 (0.48) | ALDH1A1MAPTHTTKDM4ENPC1 | |
| SCHEMBL11924095 | 0.88 | PIM2 (0.48) | ALDH1A1MAPTHTTKDM4ENPC1 | |
| SCHEMBL12831082 | 0.85 | CSF1R (0.62) | ALDH1A1MAPTHTTKDM4ENPC1 | |
| SCHEMBL11924096 | 0.82 | CHEK1 (0.65) | CHEK1PIM1PIM3PIM2 | |
| SCHEMBL11924098 | 0.79 | PIM2 (0.58) | PIM1PIM3PIM2 | |
| SCHEMBL11924097 | 0.79 | PIM2 (0.58) | PIM1PIM3PIM2 | |
| SCHEMBL16519597 | 0.77 | CHEK1 (0.82) | MAPTNPSR1CHEK1PIM1PIM3 | |
| SCHEMBL11923886 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTKDM4ENPC1 | |
| SCHEMBL11923885 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTKDM4ENPC1 | |
| SCHEMBL11924173 | 0.73 | PIM2 (0.46) | ALDH1A1MAPTHTTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025706-A2 | HETEROCYCLIC AMIDE COMPOUNDS AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2011-03-03 | — | — | WO | disclosed |