Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12830886 | 0.85 | MAOA (0.33) | — | |
| SCHEMBL12756464 | 0.83 | NPC1 (0.49) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL12830903 | 0.82 | HSD17B10 (0.38) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL12830883 | 0.81 | AKR1C3 (0.35) | — | |
| SCHEMBL12830881 | 0.79 | HTT (0.33) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL12756458 | 0.77 | NPC1 (0.49) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL12830900 | 0.77 | TMIGD3 (0.38) | NPC1RAB9AMEN1TP53KMT2A | |
| SCHEMBL12830882 | 0.74 | — | — | |
| SCHEMBL12830892 | 0.74 | ROCK2 (0.32) | — | |
| SCHEMBL12756457 | 0.74 | NPC1 (0.54) | NPC1RAB9AMEN1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |