Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | CASP7 | P55210 | 3/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24376121 | 0.69 | TDP1 (0.32) | ALDH1A1HSD17B10GPBAR1HTT | |
| SCHEMBL818744 | 0.68 | KDM4E (0.31) | ALDH1A1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL818287 | 0.67 | TDP1 (0.40) | TSHRALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL12808601 | 0.64 | NPSR1 (0.31) | ALDH1A1 | |
| SCHEMBL17787819 | 0.64 | NPSR1 (0.31) | ALDH1A1 | |
| SCHEMBL26938000 | 0.64 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL13720079 | 0.64 | KCNH2 (0.35) | TSHRHSD17B10KDM4EGAAL3MBTL1 | |
| SCHEMBL6383220 | 0.63 | HTT (0.31) | HTTSMN1; SMN2 | |
| SCHEMBL818180 | 0.62 | SLC6A3 (0.33) | SLC6A3ALDH1A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL818541 | 0.61 | NPSR1 (0.32) | TSHRSLC6A3ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292621-A1 | Vasopressin v1a antagonists | Vantia Limited (GB) | 2011-03-09 | — | — | EP | disclosed |