Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818661 | 0.80 | ALDH1A1 (0.35) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL819412 | 0.77 | ALDH1A1 (0.38) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12808601 | 0.77 | NPSR1 (0.31) | ALDH1A1 | |
| SCHEMBL17787819 | 0.77 | NPSR1 (0.31) | ALDH1A1 | |
| SCHEMBL818180 | 0.75 | SLC6A3 (0.33) | KDM4ENPC1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL818541 | 0.73 | NPSR1 (0.32) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6383220 | 0.71 | HTT (0.31) | SMN1; SMN2 | |
| SCHEMBL818287 | 0.70 | TDP1 (0.40) | KDM4EALDH1A1HSD17B10LMNANFKB1 | |
| SCHEMBL18287583 | 0.69 | CA12 (0.33) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12831900 | 0.68 | TSHR (0.32) | KDM4ESMN1; SMN2ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |