Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006836 | 0.73 | S1PR1 (0.39) | S1PR1S1PR3CYP2C9CYP2C19KMO | |
| SCHEMBL16273680 | 0.56 | KMO (0.51) | S1PR1S1PR3KMO | |
| SCHEMBL1008749 | 0.56 | POLB (0.43) | KMOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10168911 | 0.55 | CSNK2A1 (0.56) | S1PR1S1PR3KMO | |
| SCHEMBL2103199 | 0.55 | CSNK2A1 (0.61) | S1PR1S1PR3KMO | |
| SCHEMBL11619472 | 0.55 | RORC (0.40) | S1PR1S1PR3CYP2C9CYP2C19KMO | |
| SCHEMBL11619470 | 0.55 | RORC (0.40) | S1PR1S1PR3CYP2C9CYP2C19KMO | |
| SCHEMBL11619475 | 0.55 | RORC (0.40) | S1PR1S1PR3CYP2C9CYP2C19KMO | |
| SCHEMBL624873 | 0.55 | S1PR1 (0.50) | S1PR1S1PR3KMO | |
| SCHEMBL2126187 | 0.55 | S1PR1 (0.50) | S1PR1S1PR3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125789-B1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-03-16 | — | — | EP | disclosed |