Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707055 | 0.85 | CA2 (0.57) | CA2ALDH1A1CA9TSHRCA12 | |
| SCHEMBL9707060 | 0.85 | CA2 (0.57) | CA2ALDH1A1CA9TSHRCA12 | |
| SCHEMBL11456951 | 0.85 | ALDH1A1 (0.74) | CA2ALDH1A1CA9TSHRCA12 | |
| SCHEMBL8817154 | 0.81 | TDP1 (0.77) | ALDH1A1EGFRERBB2TDP1KMT2A | |
| SCHEMBL8817150 | 0.81 | TDP1 (0.77) | ALDH1A1EGFRERBB2TDP1KMT2A | |
| SCHEMBL1504320 | 0.79 | TDP1 (0.59) | ALDH1A1CA9CA12EGFRERBB2 | |
| SCHEMBL21538642 | 0.78 | CA2 (0.68) | CA2ALDH1A1CA9TSHRCA12 | |
| SCHEMBL11993560 | 0.78 | TDP1 (0.58) | ALDH1A1CA9CA12EGFRERBB2 | |
| SCHEMBL28420194 | 0.77 | CNR1 (0.54) | CA2ALDH1A1CA9TSHRCA12 | |
| SCHEMBL6329763 | 0.76 | CA2 (0.54) | CA2ALDH1A1CA9TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | CA2 1137/4885ALDH1A1 793/4885CA9 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.