Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12834309 | 0.86 | MEN1 (0.32) | DGAT1LRRK2MAPTNR3C1ALDH1A1 | |
| SCHEMBL14089977 | 0.75 | JAK2 (0.38) | DGAT1LRRK2MAPTNR3C1CA12 | |
| SCHEMBL12834316 | 0.74 | ABL1 (0.32) | NR3C1IKBKETBK1 | |
| SCHEMBL12834302 | 0.71 | F10 (0.38) | LRRK2MAPTTP53ALDH1A1MAPK1 | |
| SCHEMBL12834292 | 0.68 | CNR1 (0.44) | LRRK2MAPTLMNAALDH1A1MAPK1 | |
| SCHEMBL12834310 | 0.68 | LRRK2 (0.38) | LRRK2MAPTNR3C1ALDH1A1RAB9A | |
| SCHEMBL14089976 | 0.67 | JAK2 (0.38) | LRRK2MAPTNR3C1ALDH1A1CA2 | |
| SCHEMBL12834294 | 0.66 | KIF18A (0.33) | — | |
| SCHEMBL14091175 | 0.64 | JAK2 (0.49) | DGAT1MAPTTP53LCKHCK | |
| SCHEMBL29438430 | 0.57 | HSD17B10 (0.52) | MAPTLMNATP53NR3C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298770-A1 | Heterocyclic compounds as TrkA modulators | ChemBridge Corporation (US) | 2011-03-23 | — | — | EP | disclosed |