SCHEMBL12834396

SCHEMBL12834396

CCOc1ccc(CCC2CCC(C)CC2)c(C(F)(F)F)c1F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM1A O60341 2/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
HCRTR1 O43613 1/20 0.30
SLC6A2 P23975 5/20 0.30
SLC6A4 P31645 5/20 0.30
SLC6A3 Q01959 5/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12834395 0.91 KDM1A (0.32) ALDH1A1KDM1ASLC6A2SLC6A4SLC6A3
SCHEMBL16270061 0.88 ALDH1A1 (0.34) HPGDALDH1A1KDM1ASLC6A2SLC6A4
SCHEMBL12834379 0.88 GRIN1 (0.31) GRIN1GRIN2B
SCHEMBL1509899 0.88 ALDH1A1 (0.30) ALDH1A1
SCHEMBL13026076 0.88 GAA (0.31) HPGDSLC6A2SLC6A4SLC6A3
SCHEMBL13026113 0.88 ALDH1A1 (0.30) ALDH1A1
SCHEMBL13026084 0.85
SCHEMBL16638478 0.85 ALDH1A1 (0.35) ALDH1A1KDM1A
SCHEMBL12833697 0.84 CTSL (0.33) GRIN1GRIN2B
SCHEMBL12834715 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731493-B1 BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORP (JP) 2011-03-23 EP disclosed