Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13181493 | 0.85 | CASP1 (0.36) | CASP1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL10067132 | 0.85 | ALDH1A1 (0.34) | CASP1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL14364636 | 0.83 | ALDH1A1 (0.33) | ESRRACASP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14364638 | 0.83 | PPARG (0.32) | ESRRACASP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10067129 | 0.80 | CASP1 (0.36) | CASP1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL13181480 | 0.79 | — | — | |
| SCHEMBL10066819 | 0.79 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL14364635 | 0.79 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL14557904 | 0.79 | ELANE (0.30) | ELANE | |
| SCHEMBL14557908 | 0.79 | ELANE (0.34) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897691-B2 | Proton exchange membranes for fuel cell applications | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-03-01 | — | — | US | disclosed |