Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651823 | 0.88 | MAPT (0.39) | LMNAMAPTPKMNPC1MAOA | |
| SCHEMBL14193797 | 0.87 | LMNA (0.51) | LMNAMAPTNPC1MAOAMAOB | |
| SCHEMBL14193812 | 0.87 | LMNA (0.39) | LMNAMAPTPKMNPC1KDM4E | |
| SCHEMBL4806456 | 0.87 | NPC1 (0.48) | LMNAMAPTNPC1MAOAMAOB | |
| SCHEMBL13651772 | 0.86 | LMNA (0.50) | LMNAMAPTNPC1MAOAMAOB | |
| SCHEMBL13651773 | 0.86 | LMNA (0.50) | LMNAMAPTNPC1MAOAMAOB | |
| SCHEMBL14193810 | 0.84 | NPC1 (0.37) | LMNAMAPTPKMNPC1MAOA | |
| SCHEMBL13651779 | 0.84 | ALDH1A1 (0.49) | LMNAMAPTNPC1MAOAMAOB | |
| SCHEMBL13651821 | 0.84 | ALDH1A1 (0.36) | LMNAMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL4809265 | 0.82 | MAPT (0.35) | LMNAMAPTPKMNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298753-A1 | Novel oxetane compound, active energy ray-curable composition, active energy ray-curable ink composition and inkjet recording method | Fujifilm Corporation (JP) | 2011-03-23 | — | — | EP | disclosed |