Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.74 |
| ▸ | REN | P00797 | 1/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | RRM1 | P23921 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657427 | 1.00 | METAP2 (0.74) | METAP2RENDPP7RRM1NAAA | |
| SCHEMBL20657428 | 1.00 | METAP2 (0.74) | METAP2RENDPP7RRM1NAAA | |
| SCHEMBL7355197 | 0.85 | METAP2 (1.00) | METAP2RENNAAATSHREPHX1 | |
| Hydrochloric Acid SCHEMBL7359465 | 0.84 | METAP2 (0.97) | METAP2RENNAAATSHREPHX1 | |
| Hydrochloric Acid SCHEMBL10607147 | 0.83 | EPHX2 (0.54) | METAP2RENTSHREPHX2CHRNB2 | |
| SCHEMBL5843085 | 0.80 | METAP2 (0.48) | METAP2RENALDH1A1KMT2ACHRNB2 | |
| SCHEMBL5842745 | 0.80 | METAP2 (0.48) | METAP2RENALDH1A1KMT2ACHRNB2 | |
| SCHEMBL20657573 | 0.79 | METAP2 (0.48) | METAP2RENDPP7TSHRALDH1A1 | |
| SCHEMBL20657575 | 0.79 | METAP2 (0.48) | METAP2RENDPP7TSHRALDH1A1 | |
| SCHEMBL3911175 | 0.79 | REN (0.48) | METAP2RENDPP7CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024887-A1 | CONJUGATE CONTAINING CYCLIC PEPTIDE AND METHOD FOR PRODUCING SAME | 国立大学法人 岡山大学 (JP) | 2011-03-03 | — | — | WO | disclosed |