Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12173053 | 0.84 | KMT2A (0.78) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL9099628 | 0.81 | TSHR (0.73) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL10943491 | 0.81 | HPGD (0.78) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL9099049 | 0.77 | TSHR (0.73) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL12700202 | 0.77 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL13927144 | 0.76 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL2639485 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL9101156 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL10943133 | 0.76 | RAB9A (0.86) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL12173050 | 0.74 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026107-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-03-03 | — | — | WO | disclosed |