Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189571 | 1.00 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189643 | 1.00 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189455 | 0.84 | DGAT1 (0.48) | FAAHNR1H4 | |
| SCHEMBL12189554 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12835024 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189645 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189568 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12835052 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189542 | 0.83 | FAAH (0.56) | FAAHGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL12189418 | 0.82 | SMN1; SMN2 (0.58) | GAAS1PR1S1PR3NR1H4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026107-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-03-03 | — | — | WO | disclosed |