Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390767 | 0.85 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| Hydrochloric Acid SCHEMBL1244784 | 0.85 | GPR119 (0.67) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3495404 | 0.82 | GPR119 (0.78) | GPR119CYP2C9KCNH2 | |
| SCHEMBL28776749 | 0.80 | GPR119 (0.48) | GPR119ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27769080 | 0.77 | GPR119 (0.66) | GPR119CYP2C9KCNH2SMN1; SMN2 | |
| SCHEMBL12904116 | 0.77 | GPR119 (0.50) | GPR119ALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL1245728 | 0.75 | GPR119 (0.65) | GPR119CYP2C9KCNH2ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27659922 | 0.75 | GPR119 (0.55) | GPR119ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL1243498 | 0.73 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| Hydrochloric Acid SCHEMBL1245402 | 0.73 | GPR119 (0.69) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292620-A2 | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prohylaxis and treatment of disorders related thereto | Arena Pharmaceuticals, Inc. (US) | 2011-03-09 | — | — | EP | disclosed |