Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390767 | 0.90 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| Hydrochloric Acid SCHEMBL1244784 | 0.90 | GPR119 (0.67) | GPR119CYP2C9KCNH2 | |
| SCHEMBL288589 | 0.82 | GPR119 (0.80) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1245728 | 0.81 | GPR119 (0.65) | GPR119CYP2C9KCNH2 | |
| SCHEMBL388935 | 0.81 | GPR119 (0.98) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390855 | 0.80 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL27769086 | 0.79 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1071062 | 0.78 | GPR119 (0.75) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389364 | 0.78 | GPR119 (0.97) | GPR119CYP2C9KCNH2 | |
| SCHEMBL12835587 | 0.77 | GPR119 (0.54) | GPR119CYP2C9KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420941-A | Use of GPR119 receptor agonists for increasing bone mass and for treating osteoporosis, and related combination therapies | ARENA PHARM INC (US) | 2009-04-29 | — | — | CN | disclosed |