Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673380 | 0.92 | STAT3 (0.44) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL9782871 | 0.88 | STAT3 (0.39) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL12836206 | 0.87 | KMT2A (0.39) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL12835793 | 0.87 | STAT3 (0.38) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL1699779 | 0.82 | LMNA (0.47) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9568366 | 0.82 | MAPT (0.40) | LMNAKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL12835798 | 0.82 | STAT3 (0.35) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL9673019 | 0.81 | KDM4E (0.46) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9672976 | 0.81 | KDM4E (0.44) | STAT3LMNAADRB2KDM4EALDH1A1 | |
| SCHEMBL9674400 | 0.81 | PIM1 (0.42) | STAT3LMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031745-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |